导师简介
个人情况介绍、概览
南丽红,女,博士,教授,博士生导师,药理教研室主任。
人才称号、社会兼职等
校优势特色培育学科《中药药理学》学科带头人;中药药理学课程联盟理事;中华中医药学会中药实验药理分会委员;中华中医药学会药膳分会常委;福建省药理学会理事
主要研究方向
1、中药抗炎免疫药理
2、中药脑血管药理
主持、参与的科研项目(含科研获奖等情况)
1、国家自然科学基金委员会,面上项目,81873031,栝楼桂枝汤对缺血性脑卒中后神经元-小胶质细胞crosstalk的调控机制研究,57万元,主持
2、福建省科技厅,栝楼桂枝汤通过miR-210调控HIF-1α/VEGF信号轴影响缺血性脑卒中后血管新生的机制研究,自然科学基金面上项目,2021J01926,7万元,主持
3、福建省科技厅自然科学基金,2014J05094,基于p38MAPK信号通路的筋骨草总黄酮对肾小球系膜细胞影响的实验研究,4万元,主持
4、横向课题,消癥合剂对肾虚血瘀薄型子宫内膜大鼠的药效学研究,26万,主持
近年来发表代表性论文(限第一作者或通讯作者,SCI须写明影响因子):
(1)Gualou Guizhi Granule inhibits microglia-mediated neuroinflammation to protect against neuronal apoptosis in vitro and in vivo. Front Immunol. 2025, 15:1527986. (通讯作者,Q1,IF:5.7)
(2) Gualou Guizhi decoction promotes therapeutic angiogenesis via the miR210/HIF/VEGF pathway in vivoand in vitro, Pharmaceutical Biology, 2023, 61(1): 779-789 (通讯作者,Q1,IF:3.8 )
(3) Yaping Chen; Zheming Chen; Weineng Cheng; Yajun Cao; Wen Xu; Wenfang Lai; Yuqin Zhang; Mei Huang; Lihong Nan ; The Role of the GRP78/PERK/ATF4 Pathway in the Ability of Gua Lou Gui Zhi Decoction to Attenuate Apoptosis by Inhibiting Endoplasmic Reticulum Stress after Ischemia-Reperfusion Injury, Frontiers in Bioscience-Landmark, 2022, 27(10): 296 (通讯作者,IF:3.115 )
(4) Yaping Chen; Chuanna Liu; Kaliaperumal Kumaravel; Lihong Nan; Yongqi Tian ; Two New Sulfate-Modified Dibenzopyrones With Anti-foodborne Bacteria Activity From Sponge-Derived Fungus Alternaria sp. SCSIOS02F49, Frontiers in Microbiology, 2022, 13: 879674 (通讯作者,Q1,IF:6.064 )
(5) Lihong Nan; Qingqing Xie; Zheming Chen; Yuqin Zhang; Yaping Chen; Huang Li; Wenfang Lai; Yan Chen; Mei Huang ; Involvement of PARP1/AIF signaling pathway in protective efects of Gualou Guizhi decoction against ischemia– reperfusion injuryinduced apoptosis, Neurochemical Research, 2020, 45(2): 278-294 (第一作者,IF:3.996)
(6) Lihong Nan; Lan Yang; Yanfang Zheng; Yibo He; Qingqing Xie; Zheming Chen; Huang Li; Mei Huang ; Effects of Gualou Guizhi Decoction Aqueous Extract on Axonal Regeneration in Organotypic Cortical Slice Culture after Oxygen-Glucose Deprivation, Evidence-Based Complementary and Alternative Medicine, 2017, 2017(1): 1-11 (第一作者,IF:2.064 )
(7)Impacts of the serum containing total flavonoids of Ajugaon rat glomerular mesangial cells, Molecular Medicine Reports, 2017, 16(4): 4895-4902 (第一作者,IF:1.922 )
主编或参编的教材、专著
1、《中药药理学》科学出版社,十四五规划教材,参编,2022
2、《中药毒理学》上海科技出版社,十四五规划教材,参编,2023
3、《药理学》科学出版社,十四五规划教材,参编,2023
4、《中药毒理学》科学出版社,十四五规划教材,参编,2024
专利及其他
一种治疗脑卒中的药物组合物及其制备方法和用途, 2023.8, ZL202310356530.9